How could Myfortic® make the difference for your transplant care?
Myfortic® remains intact in the acid environment of the stomach with a pH <5 1
Myfortic® only allows MPA release until it reaches the small intestine with an environment pH >5 1
MPA release over time for Myfortic® 360 mg tablets at pH 5.0-6.8 1
Myfortic ® and MMF provide similar MPA exposure (AUC) in renal transplant patients 1
Myfortic ® sustains MPA exposure even when co-administered with PPI 2
Abbreviations:
MMF: mycophenolate mofetil; GI: gastrointestinal; MPA: mycophenolic acid; AUC: area under the curve; NS: non-significant
References:
1. Arns W, et al. Clin Transplant. 2005;19(2):199-206 2. Rupprecht K, et al. J Clin Pharmacol. 2009;49(10):1196-1201.
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